Remote workers miss out on lots of different social interactions, often spontaneous, that can form when everyone is co-located. Especially when working on a difficult problem, or when facing a stressful situation, it's possible to become trapped by the context. Without appropriate levels of support, people can become quite lonely.
In comparison, Remote working can be isolating and lonely as these interactions are lost completely.
Remote working can be isolating and lonely, especially for those who live alone or will continue to shield for health reasons (without government support).
Remote workers must compete to be heard, and their exclusion can contribute to Remote working can be isolating and lonely.